Societá

Attivitá SIGG

Giornale di Gerontologia

Numero 3, Giugno 2010 - Volume LVIII

Copertina

Sommario

Editoriale

Il controllo glicemico nell´anziano diabetico: cosa ci insegnano i risultati dei trials?

L.J DOMINGUEZ, G. PAOLISSO*, M. BARBAGALLO
Cattedra di Geriatria, Universitá di Palermo;
* Cattedra di Geriatria, Universitá di Napoli

G GERONTOL 2010;58:127-130

Parole chiave: Ipoglicemia - Diabete tipo 2 - Anziano - Demenza - Inibitori della DPP-4 - Incretino mimetici
Key words: Hypoglycemia - Type 2 diabetes - Elderly - Dementia - DPP-4 inhibitors - Incretin mimetics

Articoli daggiornamento

Sezione Gerontologia Psico-sociale
La dimensione religiosa/spirituale nelle demenze


G. CIPRIANI, G. BORIN*
Neurologo, Referente uVA ASL 12 Viareggio;
* Sociologa, Universitá di Pisa

G GERONTOL 2010;58:184-187

Parole chiave: Religione - Spiritualitá - Cura spirituale - Demenza
Key words: Religion - Spirituality - Spiritual care - Dementia

Articoli originali

Sezione clinica
Elevati livelli plasmatici delle forme di vitamina E e riduzione del rischio di malattia di Alzheimer in etá avanzata


F. DI FELICE*, F. MANGIALASCHE* **, M. KIVIPELTO**, L. PELINI*, D. RIZZUTO**, K. PALMER** ***, B. WINBLAD**, P. MECOCCI*, L. FRATIGLIONI**
* Istituto di Gerontologia e Geriatria, Dipartimento di Medicina Interna Sperimentale, Universitá di Perugia;
** Aging Research Center, Karolinska Institutet, Stoccolma, Svezia;
*** Dipartimento di Neuropsicologia, IRCCS Fondazione Santa Lucia, Roma

G GERONTOL 2010;58:131-140

Sezione Clinica
La clinical governance del paziente anziano nell´ambulatorio del Medico di Medicina Generale


F. SARDI* **, S. SANTACROCE***, G. RICEVUTI* **
*Dipartimento di Medicina Interna e Terapia Medica, Sezione di Geriatria e Gerontologia, Universitá di Pavia, Divisione Clinicizzata di Geriatria e Gerontologia, IDR ″Santa Margherita″ - Pavia;
**Laboratorio di Fisiopatologia Cellulare ed Immunologia Clinica, Fondazione IRCCS San Matteo, Pavia;
***Medico di Medicina Generale - ASL Pavia

G GERONTOL 2010;58:141-150

Sezione clinica
La prescrizione inappropriata di farmaci in pazienti anziani ospiti di residenza


A. ELMO, C. RUGGIERO, G. DELL´AQUILA, B. GASPERINI, A. CHERUBINI
Istituto di Gerontologia e Geriatria, Universitá di Perugia

G GERONTOL 2010;58:151-161

Older people consume a large proportion of health care, including drugs, and evidence shows that drug prescribing to this group is often inappropriate.
Negative consequences of potential inappropriate drug prescription (PIDP) include adverse drug events, higher health care service utilization and higher costs for the patient and society. Although nursing home residents are the most vulnerable persons exposed to PIDP, few observational studies investigated the prevalence, the factors associated with and the consequences of PIDP. Epidemiological studies assessing the PIDP mainly based on the Beers criteria showed that about half of the U.S. and Canadian nursing home residents have at least one PIDP in this setting. The most frequent inappropriate prescriptions concern the neuroleptic and long-term benzodiazepines.
Nursing home residents aged 80 or more years, those with a low number of drugs, cognitive or communication problems, are less exposed to PIDP as compared with those younger than 80 years, living in facilities with high number of beds and lower registered nurse-to-resident ratio. In European countries, the prevalence of PIDP among elderly nursing home residents was comparable or higher to that observed in U.S. and Canadian nursing homes.
To date, no published study addressed the issue of PIDP in a representative sample of Italian nursing home residents. In a preliminary study performed in 496 nursing home residents randomly selected from 40 nursing homes in Umbria, the prevalence of residents taking at least one and two inappropriate medications was 28% and 7%, respectively. The prevalence of PIDP considering diagnosis (18%) as well as those regardless of diagnosis (17%), as determined by Beers criteria were equally distributed in older Italian nursing home residents and no difference was found between sexes. Overall, this review reveals that the prevalence of PIDP is high in both North American and European nursing homes and highlights the urgent need for intervention trials testing strategies to reduce the health and social burden of PIDP.

Key words: Inappropriate drug prescription - Nursing home - Older - Beers criteria

Sezione Clinica
Valutazione dello stato nutrizionale in una popolazione di soggetti anziani: correlazione del MNA con altre aree dimensionali geriatriche


M.E. PAIS, M.G. CONGIU, A. SABA, M. ARESU, A.L. BRUNDU, S. CADEDDU, S. CAPPAI, R.V. CARIA, M. COCCO, E. CORDA, N.M.C. CURRELI, D. IBBA, N. MUAKA, A. LA SALA, E. PEDDITZI, M. PINTUS, E. TROGU, A. MANDAS
Dipartimento di Scienze Mediche Internistiche, Scuola di Specializzazione in Geriatria, Universitá di Cagliari

G GERONTOL 2010;58:162-167

Sezione Sociocomportamentale
Sintomatologia depressiva: prevalenza e significato in riabilitazione geriatrica


M. COLOMBO* **, M. COTTINO*, D. FERRARI*, G. PROCINO*, G. PREVIDERÉ*, M. CAIRATI*, A. CERETTI*, A. GUAITA* **
* Istituto Geriatrico ″Camillo Golgi″, ** Fondazione ″Golgi Cenci″, Abbiategrasso (MI)

G GERONTOL 2010;58:168-172

Sezione Biogerontologia
I limiti del resveratrolo: per una sicura azione antiossidante é necessaria la co-presenza dei polifenoli del vino rosso


S. STRANIERO, G. CAVALLINI, A. DONATI, E. BERGAMINI
Centro di Ricerca di Biologia e Patologia dell´Invecchiamento, Universitá di Pisa

G GERONTOL 2010;58:173-178

There is evidence that a diet rich in fruit and vegetables may reduce the risk of age-associated diseases. It has been suggested that benefits associated with fruit and red wine consumption could be due to the antioxidant pool of diet microcomponents. In this study, the antioxidant activities of trans-resveratrol (a well known phytoalexin) and red wine polyphenols (RWP) were investigated in UVB-radiated isolated rat liver cells. RWP protected liver cells from photolipoperoxidation at any dosage, and the effect increased with dosage. Resveratrol by itself had pro-oxidant or antioxidant effects depending on the lower or higher dosage. Combinations of the two compounds inhibited synergistically the oxidative injury of membrane lipids, and resveratrol exhibited anti-oxidant activity both at the higher and lower dosage. The conclusion is that the administration of resveratrol is always safe and beneficial only when the drug is given together with RWP.

Key words: Resveratrol - Red wine polyphenols - Vitamin E - CoQ - Dolichol - UVB radiation - Oxidative stress - MDA

Articoli originali brevi

Sezione Sociocomportamentale
La fragilitá nella popolazione anziana: analisi della letteratura dal 1983 al 2009


A. MARCON, A. ACCORSI*, F. DI TOMMASO*, P. FALASCA*, A. BERARDO*, E. QUARGNOLO**
Dottore di Ricerca in Psicologia Sociale, operante in Azienda uSL di Ravenna e in Friuli Venezia Giulia;
* Servizio Epidemiologia, Ricerca e Sviluppo, Azienda uSL di Ravenna;
** Direttore Servizi Socio Sanitari, Azienda usl di Ravenna

G GERONTOL 2010;58:179-183